List of contributors, v <p>Preface, ix</p> <p>List of abbreviations, xi</p> <p><b>Part 1 Understanding evidence and pain, 1</b></p> <p>1 Why evidence matters, 3<br /> <i>Andrew Moore and Sheena Derry</i></p> <p>2 Clinical trial design for chronic pain treatments, 14<br /> <i>Alec B. O’Connor and Robert H. Dworkin</i></p> <p>3 Introduction to evaluation of evidence, 31<br /> <i>Eija Kalso</i></p> <p>4 Neurobiology of pain, 42<br /> <i>Victoria Harvey and Anthony Dickenson</i></p> <p>5 Intractable pain and the perception of time: every patient is an anecdote, 52<br /> <i>David B. Morris</i></p> <p>6 Psychology of chronic pain and evidence-based psychological interventions, 59<br /> <i>Christopher Eccleston</i></p> <p><b>Part 2 Clinical pain syndromes: the evidence, 69</b></p> <p>7 Chronic low back pain, 71<br /> <i>Maurits van Tulder and Bart Koes</i></p> <p>8 Chronic neck pain and whiplash, 83<br /> <i>Allan Binder</i></p> <p>22 Headache, 279<br /> <i>Peer Tfelt-Hansen</i></p> <p>23 Chest pain syndromes, 292<br /> <i>Austin Leach and Michael Chester</i></p> <p><b>Part 3 Cancer pain, 309</b></p> <p>24 Oncologic therapy in cancer pain, 311<br /> <i>Rita Janes and Tiina Saarto</i></p> <p>25 Cancer pain: analgesics and co-analgesics, 327<br /> <i>Rae Frances Bell</i></p> <p>26 Psychologic interventions for cancer pain, 337<br /> <i>Francis J. Keefe, Tamara J. Somers and Amy Abernethy</i></p> <p>27 Transcutaneous electrical nerve stimulation and acupuncture, 348<br /> <i>Mark I. Johnson</i></p> <p><b>Part 4 Treatment modalities: the evidence, 367</b></p> <p>28 Interventional therapies, 369<br /> <i>Anthony Dragovich and Steven P. Cohen</i></p> <p>29 Spinal cord stimulation for refractory angina, 400<br /> <i>Mats Börjesson, Clas Mannheimer, Paulin Andréll and Bengt Linderoth</i></p> <p>30 Rehabilitative treatment for chronic pain, 407<br /> <i>James P. Robinson, Raphael Leo, Joseph Wallach, Ellen McGough and Michael Schatman</i></p> <p>31 Drug treatment of chronic pain, 424<br /> <i>Henry McQuay</i></p> <p>32 Complementary therapies for pain relief, 434<br /> <i>Edzard Ernst</i></p> <p>Index, 439</p>